A - Human Necessities – 61 – P
Patent
A - Human Necessities
61
P
A61P 15/10 (2006.01) A61K 31/185 (2006.01) A61K 45/06 (2006.01)
Patent
CA 2453572
The invention relates to the use of 2,5-dihydroxybenzenesulphonic acid derivatives having general formula (I) in the production of medicaments that are used in therapeutics in order to potentiate the effects of inhibitors of phosphodiesterase-5 including sildenafil, vardenafil and IC-351, apomorphine, nitric oxide including amyl nitrate, nitroglycerine, nitroprusside, nitrosothiol and nicorandil, compounds that increase the cyclic GMP level in the penile tissue and other compounds that are intended to stimulate penile erection in men. (Formula I).
L'invention concerne l'utilisation de dérivés d'acides 2,5-dihydroxybenzénosulfoniques représentés par la formule générale (I), dans laquelle l'élaboration de médicaments utiles en thérapeutique pour stimuler les effets des inhibiteurs de la phosphodiestérase-5, notamment le sildenafile, vardenafile et IC-351, de l'apomorphine, des donneurs d'oxyde nitrique, notamment le nitrate d'amyle, la nitroglycérine, le nitroprusiate, les nitrosothiols et le nicorandile, des composés qui augmentent le niveau de GMP cyclique dans le tissu pénien et d'autres composés destinés à stimuler l'érection du pénis chez l'homme. (Formule I).
Esteve-Soler Jose
Saenz de Tejada-Gorman Inigo
Fetherstonhaugh & Co.
Laboratorios Del Dr. Esteve S.a.
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