The use of enzymatic resolution for the preparation of...

Details The use of enzymatic resolution for the preparation of... The use of enzymatic resolution for the preparation of...

C - Chemistry, Metallurgy

12

P

C12P 13/00 (2006.01) C12P 13/02 (2006.01)

Patent

CA 2649117

Provided is the use of enzymatic resolution for the preparation of intermediates of pregabalin, including (3S)-cyano-5-methylhexanoic acid and salts thereof and R-(-)-3-(carbamoylmethyl)-5-methylhexanoic acid and salts thereof.

La présente invention concerne l'utilisation de la résolution enzymatique pour la préparation d'intermédiaires de prégabaline, comprenant l'acide (3S)-cyano-5-méthylhexanoïque et des sels de celui-ci et l'acide R-(-)-3-(carbamoylméthyl)-5-méthylhexanoïque et des sels de celui-ci.

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