The use of free radical scavengers for protecting and...

A - Human Necessities – 61 – K

Patent

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Details

A61K 45/08 (2006.01) A61K 31/353 (2006.01) A61K 35/64 (2006.01) A61K 36/06 (2006.01) A61K 36/185 (2006.01) A61K 38/17 (2006.01) A61K 47/02 (2006.01) A61K 47/40 (2006.01) A61K 47/46 (2006.01) A61P 17/00 (2006.01) A61P 17/14 (2006.01) A61P 39/06 (2006.01)

Patent

CA 2607237

The present invention relates to the use of one or more free radical scavengers as prophylactically or therapeutically effective substances and microparticles having an average particle size ranging from 5 to 200 ~m for the preparation of a topical pharmaceutical composition for the protection or treatment of skin or hair damages caused by chemotherapeutic treatment. The invention also concerns a method for the protection or treatment of skin and hair damages of a mammal caused by chemotherapy. The invention further relates to a kit for the protection or treatment of hair damages caused by chemotherapeutic treatment consisting of a topical composition comprising microparticles together with free radical scavengers and a shampoo for an effective hair cleaning and supporting the hair treatment. A kit for the protection or treatment of skin damages caused by chemotherapy consisting of a topical composition comprising microparticles together with free radical scavengers and a cleansing milk for an effective skin cleaning and supporting the skin treatment is a further object of the present invention.

L'invention concerne l'utilisation d'au moins un piégeur de radicaux libres comme substance prophylactiquement ou thérapeutiquement efficace et de particules présentant une taille moyenne comprise entre 5 et 200 ?m dans la préparation d'une composition pharmaceutique topique destinée à protéger la peau ou les cheveux ou à traiter les dommages causés à la peau ou aux cheveux par un traitement chimiothérapeutique. L'invention concerne également un procédé de protection de la peau et des cheveux d'un mammifère ou de traitement des dommages causés à la peau et aux cheveux d'un mammifère par la chimiothérapie. L'invention concerne encore un kit de protection des cheveux ou de traitement des dommages causés aux cheveux par un traitement chimiothérapeutique, constitué d'une composition topique contenant des microparticules associées à des piégeurs de radicaux libres, et d'un shampooing nettoyant efficacement les cheveux et favorisant le traitement des cheveux. L'invention concerne enfin un kit de protection de la peau ou de traitement des dommages causés à la peau par la chimiothérapie, constitué d'une composition topique contenant des microparticules associées à des piégeurs de radicaux libres et d'un lait nettoyant efficacement la peau et favorisant le traitement de la peau.

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