C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/54 (2006.01) A01K 67/027 (2006.01) A61K 31/70 (2006.01) A61K 35/12 (2006.01) A61K 35/28 (2006.01) A61K 38/45 (2006.01) A61K 48/00 (2006.01) C12N 15/85 (2006.01)
Patent
CA 2236982
This invention provides methods for treating atherosclerosis in a mammalian subject by increasing the activity of LCAT in the serum of the subject to a level effective to decrease the accumulation of cholesterol in the subject. Pharmaceutical dosage forms containing LCAT also are provided.
On décrit des procédés permettant de traiter l'athérosclérose chez un mammifère en augmentant l'activité de la lécithine-cholestérol acyltransférase (LCAT) dans le sérum d'un tel sujet, jusqu'à un niveau efficace pour réduire l'accumulation de son cholestérol. On décrit aussi des formes galéniques pharmaceutiques contenant de la LCAT.
Brewer H. Bryan Jr.
Hoeg Jeffrey M.
Santamarina-Fojo Silvia
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Department Of Health And Human Services The Government Of The United States Of America Represented By Th
The Government Of The United States Of America Represented By Th
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