A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/54 (2006.01) A61K 31/4439 (2006.01) A61P 9/10 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2526816
The invention relates to the use of lornoxicam or analogues thereof which inhibit cyclo-oxygenase 1 and cyclo-oxygenase 2 (COX 1 and COX 2), cannot penetrate the blood-brain barrier under physiological conditions, and reduce the prostaglandin E2-induced induction of the amyloid-precursor-protein (APP), for producing a pharmaceutical composition for the treatment or prevention of Alzheimer's disease or arteriosclerosis.
L'invention concerne l'utilisation de lornoxicam ou d'analogues de lornoxicam, qui inhibent la cyclo-oxygénase 1 et la cyclo-oxygénase 2 (COX 1 et COX 2), qui ne peuvent pas franchir la barrière hémato-encéphalique dans des conditions physiologiques et qui réduisent l'induction, par la prostaglandine E2, de la protéine précurseur amyloïde (APP), pour produire une composition pharmaceutique servant à traiter ou à prévenir la maladie d'Alzheimer ou l'artériosclérose.
Binder Eva
Dritte Patentportfolio Beteiligungsgesellschaft Mbh & Co. Kg.
Fetherstonhaugh & Co.
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