The use of plant oil-bodies in vaccine delivery systems

A - Human Necessities – 61 – K

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Details

A61K 39/39 (2006.01) A61K 39/00 (2006.01) A61K 39/385 (2006.01) A61P 37/04 (2006.01) C07K 14/415 (2006.01) C07K 19/00 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2411965

The present invention relates to the use of oil bodies as a vaccine adjuvant and delivery system for administration of vaccines by parenteral, mucosal (oral, nasal, pulmonary) and transdermal routes. In addition, the present invention relates to methods of eliciting an immune response in an animal by administering oil body-antigen complexes to said mammal. Finally, the present invention relates to methods of preparing oil body-antigen complexes.

La présente invention concerne l'utilisation de corps lipidiques végétaux comme adjuvants vaccinaux et systèmes d'administration pour l'administration de vaccinaux par voie parentérale, muqueuse (orale, nasale, pulmonaire) et percutanée. L'invention concerne en outre des procédés pour susciter chez un animal une réponse immunitaire en administrant à ce mammifère des complexes de corps lipidique et d'antigène. L'invention concerne enfin des procédés pour l'élaboration de tels complexes de corps lipidique et d'antigène.

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