The use of polymers for inhibiting the denaturation of...

C - Chemistry – Metallurgy – 08 – J

Patent

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C08J 7/12 (2006.01) A61L 27/00 (2006.01) A61L 29/00 (2006.01) A61L 31/00 (2006.01) A61L 33/00 (2006.01) C07K 1/113 (2006.01) C07K 14/75 (2006.01) C07K 14/765 (2006.01) C08L 101/04 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2239140

Disclosed is a shaped article which comes into contact with a native protein and prevents denaturation of the protein when in use. The article is made of a polymer or has a part made of the polymer. The polymer has at least in a surface layer thereof, structural units having one, two or three fluorine atoms on a first carbon atom which is bonded to a second carbon atom which carries a hydroxyl group and being furthermore substituted by another trifluoromethyl group when the first carbon atom carries three fluorine atoms.

Divulgation d'un article profilé qui entre en contact avec une protéine native et empêche la dénaturation de celle-ci pendant son utilisation. L'article est fabriqué d'un polymère ou comporte une partie en polymère. Le polymère a au moins, dans une couche superficielle, des unités structurales ayant un, deux ou trois atomes de fluor sur un premier atome de carbone lié à un second atome de carbone qui porte un groupement hydroxyle, substitué de surcroît par un autre groupement trifluorométhyle lorsque le premier atome de carbone porte trois atomes de fluor.

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