The use of pregnane and androstane steroids for the...

C - Chemistry – Metallurgy – 07 – J

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C07J 7/00 (2006.01) A61K 31/568 (2006.01) A61K 31/5685 (2006.01) A61K 31/57 (2006.01) A61P 25/00 (2006.01) A61P 25/10 (2006.01) A61P 25/28 (2006.01) C07J 1/00 (2006.01) C07J 41/00 (2006.01)

Patent

CA 2664126

Steroid compounds having increased resistance against metabolism and increased water solubilit y are disclosed, together with methods for their production. These substances are suitable for the manufacture of pharmaceuticals for the treatment of steroid related or steroid induced CNS disorders and for use in methods of prevention, alleviation or treatment of such disorders.

L'invention concerne des composés stéroïdes ayant une résistance accrue vis-à-vis du métabolisme et une solubilité dans l'eau accrue, ainsi que des procédés pour la production de ceux-ci. Ces substances conviennent pour la fabrication de produits pharmaceutiques pour le traitement de troubles du système nerveux central (SNC) liés aux stéroïdes ou induits par des stéroïdes et pour être utilisées dans des procédés de prévention, de soulagement ou de traitement de tels troubles.

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