The use of quaternary pyridinium compounds for...

A - Human Necessities – 61 – K

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A61K 31/4425 (2006.01) A61K 31/444 (2006.01) A61P 1/16 (2006.01)

Patent

CA 2714601

The invention relates to the use of a compound selected from the group consisting of. Formula (I), Formula (II) and Formula (III), wherein R represents hydrogen atom, CH3, OH, pyridyl (C5H4N), 1- methylpyridyl (C5H4N-CH3) or pyridyl substituted with hydroxy group ((OH)C5H3N), and X represents a physiologically acceptable counterion, for the treatment or prevention of diseases or conditions associated with vascular endothelium dysfunction or liver injury.

L'invention porte sur l'utilisation d'un composé choisi dans le groupe constitué par : Formule (I), Formule (II) et Formule (III), où R représente un atome d'hydrogène, OH, pyridyle (C5H4N), 1-méthylpyridyle (C5H4N-CH3) ou pyridyle substitute par un groupe hydroxy ((OH)C5H3N), et X représente un contre-ion physiologiquement acceptable, pour le traitement ou la prévention de maladies ou d'états associés à un dysfonctionnement de l'endothélium vasculaire ou à une lésion du foie.

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