The use of substances for the treatment of loss of eyesight...

A - Human Necessities – 61 – K

Patent

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A61K 38/08 (2006.01) A61P 27/06 (2006.01)

Patent

CA 2688215

Methods for the prevention and treatment of ocular disorders, in particular glaucoma, through blocking the toxic effects of beta-amyloid (Abeta) derivatives by use of a peptide comprising amino acid sequence X-Y or Y-X, wherein X is an aromatic amino acid and Y is one or more additional amino acid other than glycine, the peptide having at.least 2 amino acid residues and less than 15 amino acid residues. Further, pharmaceutical compositions for effecting such prevention and treatment thereof are claimed.

L'invention porte sur des procédés pour la prévention et le traitement de troubles oculaires, en particulier un glaucome, par le blocage des effets toxiques des dérivés de .beta.-amyloïde (A.beta.), et sur des compositions pharmaceutiques pour effectuer une telle prévention et un tel traitement apparentés.

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