A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/16 (2006.01) A61P 1/12 (2006.01) A61P 31/04 (2006.01)
Patent
CA 2693047
The present invention provides methods for the treatment or prophylaxis of a microbial infection of the lower in-testine or colon in a subject, the method comprising administering to the subject a type-B lantibiotic. In particular, the invention provides methods for the treatment or prophylaxis of a Clostridium difficile infection. The type-B lantibiotics may include com-pounds selected from the group consisting of mersacidin, actagardine, plantaricin, planosporicin, ruminococcin, antibiotic 10789, michiganin and haloduracin, and derivatives and variants thereof.
L'invention concerne des procédés de traitement ou de prophylaxie d'une infection microbienne de l'intestin grêle ou du côlon chez un sujet, ce procédé consistant à administrer au sujet un lanthibiotique de type B. Cette invention concerne, plus particulièrement, des procédés de traitement ou de prophylaxie d'une infection à Clostridium difficile. Les lanthibiotiques de type B peuvent contenir des composés sélectionnés dans le groupe constitué de mersacidine, d'actagardine, de plantaricine, de planosporicine, de ruminococcine, de l'antibiotique 10789, de michiganine et d'haloduracine, ainsi que des dérivés et des variants de ceux-ci.
Cortes Bargallo Jesus
Dawson Michael John
Wadman Sjoerd Nicolaas
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Novacta Biosystems Limited
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