A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/19 (2006.01)
Patent
CA 2335641
This invention relates to a method for the treatment and prevention of migraine and affective illness by administering a therapeutically effective amount of the valproic acid analog 2-n-propyl-4-hexynoic acid. The compound 2- n-propyl-4-hexynoic acid is an effective anti-migraine and anti-affective illness drug with greatly reduced adverse effects including neurotoxicity and teratogenic potential compared to valproic acid. This invention thus provides an improved method for treating and preventing migraine and affective illness.
L'invention a trait à une méthode de traitement et de prévention de la migraine et de maladies affectives, par l'administration d'une quantité thérapeutiquement efficace de l'analogue d'acide valproïque, l'acide 2-n-propyl-4-hexynoïque. Le composé d'acide 2-n-propyl-4-hexynoïque constitue un médicament efficace contre la migraine et les maladies affectives, qui présente des effets secondaires considérablement réduits, notamment une neurotoxicité et un potentiel tératogène réduits par comparaison avec l'acide valproïque. L'invention concerne par conséquent une méthode améliorée de traitement et de prévention de la migraine et de maladies affectives.
Leahy Emer
Nau Heinz
O'connell Alan
American Biogenetic Sciences Inc.
Nau Heinz
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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