Theophyllinemethyldithiolan and theophyllinemethyldithianyl...

C - Chemistry – Metallurgy – 07 – D

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C07D 473/08 (2006.01) A61K 31/52 (2006.01)

Patent

CA 1284996

ABSTRACT New derivatives of theophylline are described, which have the general formula: (I) Image in which R is selected from the group consisting of 2'- (1'-oxy-1', 3'-dithiolanyl), 2'-(1', 3'-dithiolanyl) and 2'-(1',3'-dithianyl), possibly substituted in position 4', The derivatives have high antibronchospastic, antitussive and mucolytic activities.

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