Therapeutic agent

Details Therapeutic agent Therapeutic agent

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 31/7088 (2006.01) A61K 31/713 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 3/04 (2006.01) A61P 9/00 (2006.01) A61P 19/02 (2006.01) A61P 19/10 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07K 14/705 (2006.01) C07K 14/72 (2006.01) C07K 16/28 (2006.01) C12N 5/16 (2006.01) C12N 15/13 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) C07K 14/585 (2006.01)

Patent

CA 2624931

The present invention relates to agents which modulate the effect of a RAMP (Receptor Activity MoifyingProtein) protein on a Calcitonin Receptor Like Receptor (CRLR). Also included in the present invention are methods and uses of such agents and assays for identifying such agents. The agents of the present disclosure may be used in the treatment of, for example, cancer, obesity and other disorders.

L'invention se rapporte à des agents qui modulent l'effet de la protéine RAMP (protéine modifiant l'activité du récepteur) sur un récepteur apparenté au récepteur de la calcitonine (CRLR). L'invention concerne également des procédés et des utilisations de ces agents, et des méthodes permettant d'identifier de tels agents. Ces agents peuvent être utilisés par exemple pour le traitement du cancer, de l'obésité et d'autres troubles.

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