Therapeutic agent for bladder hypersensitivity

Details Therapeutic agent for bladder hypersensitivity Therapeutic agent for bladder hypersensitivity

A - Human Necessities

61

K

A61K 31/55 (2006.01) A61P 13/08 (2006.01) A61P 13/10 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2442468

Remedies for vesical hyperesthesia which contain as the active ingredient tricyclic compounds represented by the following general formula (I) or pharmacologically acceptable salts thereof: (I) wherein R1 represents hydrogen, optionally substituted lower alkyl, etc.; X1-X2-X3 represents CR5=CR6-CR7=CR8, CR5=CR6-S, etc.; Y represents -CH2S-, SOCH2, etc.; and R2 represents hydrogen, etc.

L'invention concerne des médicaments contre l'hyperesthésie vésicale, ces médicaments contenant comme ingrédient actif des composés tricycliques, ou des sels pharmacologiquement acceptables de ceux-ci, représentés par la formule générale (I) suivante, dans laquelle R¿1? représente hydrogène, alkyle inférieur facultativement substitué, etc.; X¿1?-X¿2?-X¿3? représente CR¿5?=CR¿6?-CR¿7?=CR¿8?, CR¿5?=CR¿6?-S, etc.; Y représente -CH¿2?S-, SOCH¿2?, etc.; et R¿2? représente hydrogène, etc.

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