Therapeutic agent for cartilaginous diseases

A - Human Necessities – 61 – K

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Details

A61K 38/18 (2006.01) C07K 14/475 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2197869

The present invention relates to a therapeutic agent for cartilaginous diseases, an accelerator for chondrocyte proliferation and an accelerator for proteoglycan production comprising HGF (hepatocyte growth factor) as an active component, and a treatment method for cartilaginous diseases of human or mammals comprising administering an effective amount of HGF. The active component HGF has an effect to promote the proliferation of chondrocytes and to promote the production of proteoglycan. Therefore, the therapeutic agent and accelerator of the present invention are useful for the prevention and treatment of various disorders caused by cartilaginous diseases.

Remède ou maladie des cartilages, accélérateur de croissance des cellules de cartilage et accélérateur de formation de protéoglycane, renfermant chacun un facteur de croissance des hépatocytes (HCF) comme principe actif, et méthode de traitement des maladies des cartilages humains et mammaliens par administration d'une dose efficace de HGF. En tant que principe actif, le HGF accélère la croissance des cellules de cartilage et la formation de protéoglycane. Ce remède et ces accélérateurs sont ainsi utiles pour la prévention et le traitement de diverses maladies des cartilages.

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