C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/04 (2006.01) A61K 31/506 (2006.01) A61P 9/10 (2006.01) C07D 401/12 (2006.01) C07D 487/08 (2006.01)
Patent
CA 2687942
It is intended to provide a novel therapeutic agent for cerebral infarction containing a piperazine compound as an active ingredient. The compound according to the invention can be formulated into a novel therapeutic agent for cerebral infarction having an effect of reducing the volume of brain injury or improving neurologic symptoms by suppressing the production of a plurality of inflammatory cytokines and chemokines present in the brain such as TNF-.alpha., IL-1.beta., IL-6 and MCP-1.
La présente invention concerne un nouvel agent thérapeutique pour un infarctus cérébral contenant un composé de pipérazine en tant que principe actif. Le composé selon l'invention peut être formulé en un nouvel agent thérapeutique pour un infarctus cérébral ayant pour effet une réduction du volume de la lésion cérébrale ou une amélioration des symptômes neurologiques en réprimant la production de toute une pluralité de cytokines et de chimiokines inflammatoires présentes dans le cerveau telles que le TNF .alpha., l'IL-1.beta., l'IL-6 et la MCP-1.
Ando Naoko
Nakagawa Haruto
Fetherstonhaugh & Co.
Mitsubishi Tanabe Pharma Corporation
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