Therapeutic agent for chronic obstructive pulmonary disease...

A - Human Necessities – 61 – K

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A61K 31/4704 (2006.01) A61P 11/00 (2006.01) C07D 215/38 (2006.01)

Patent

CA 2533919

This therapeutic agent for chronic obstructive pulmonary disease comprises, an active ingredient, at least one of a 7-aminoquinolinone derivative represented by the general formula (I): (see formula I) wherein R1 represents a hydrogen atom or an alkyl group; R2 and R3 each represents a group selected from a hydrogen atom, an acyl group, an alkyl group and an alkenyl group; and R4 and R5 each represents a group selected from a hydrogen atom, an acyl group, an alkyl group, an alkenyl group and an aralkyl group, and its physiologically acceptable salt.

L'invention concerne un agent thérapeutique pour des maladies pulmonaires obstructives chroniques. Cet agent contient, en tant que principe actif, au moins soit, un dérivé 7-aminoquinolinone de formule (I), ou un sel physiologiquement acceptable de ce dérivé. Dans cette formule, R¿1? désigne hydrogène ou alkyle ; R¿2? et R¿3? désignent chacun un élément sélectionné parmi : hydrogène, acyle, alkyle et alcényle ; et R¿4? et R¿5? désignent chacun un élément sélectionné parmi : hydrogène, acyle, alkyle, alcényle, et aralkyle.

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