A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/519 (2006.01) A61P 17/00 (2006.01)
Patent
CA 2344182
The present invention provides a therapeutic agent for dermatitis, particularly a therapeutic agent for atopic dermatitis, having high safety and showing little adverse reaction such as steroidal agent. The present invention relates to a therapeutic agent for dermatitis, particularly a therapeutic agent for atopic dermatitis, containing a compound represented by the following formula (I) or a pharmaceutically acceptable salt or hydrate thereof as an effective ingredient. (see formula I) (In the formula, R is hydrogen or halogen.) The therapeutic agent for dermatitis according to the present invention significantly and dose-dependently suppressed the antigen-induced swelling reaction in a mouse ear recognized as an animal model for atopic dermatitis. Also, the agent suppressed the antigen-induced flare reaction of mice occurred with the swelling reaction. In addition, the adverse reaction to the skin was not observed. The therapeutic agent for dermatitis of this invention is, therefore, very useful as a drug for atopic dermatitis with high safety.
Fujita Akihiro
Yoshii Haruo
Kirby Eades Gale Baker
Nippon Zoki Pharmaceutical Co. Ltd.
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