Therapeutic agent for nausea and/or vomiting

Details Therapeutic agent for nausea and/or vomiting Therapeutic agent for nausea and/or vomiting

A - Human Necessities

61

K

A61K 31/485 (2006.01) A61P 1/08 (2006.01) C07D 489/08 (2006.01)

Patent

CA 2625495

Disclosed is a therapeutic and/or prophylactic agent for nausea and/or vomiting. The therapeutic and/or prophylactic agent comprises a compound represented by the formula (I), a pharmaceutically acceptable salt of the compound, or a solvate of the compound or salt: (I) wherein represents or ; R1 and R2 independently represent a hydrogen or a lower alkyl; R3 represents a hydrogen or a lower alkoxycarbonyl; and R4 represents a hydrogen or a lower alkyl; provided that not all of R1 to R4 represent a hydrogen and not both of R1 and R4 represent a hydrogen.

La présente invention concerne un agent thérapeutique et/ou prophylactique contre la nausée et/ou le vomissement. L'agent thérapeutique et/ou prophylactique comprend un composé représenté par la formule (I), un sel pharmaceutiquement acceptable du composé ou un solvate du composé ou du sel : (I) dans laquelle R1 et R2 représentent indépendamment un hydrogène ou un alkyle inférieur ; R3 représente un hydrogène ou un alcoxycarbonyle inférieur ; et R4 représente un hydrogène ou un alkyle inférieur ; à condition que les R1 à R4 ne représentent pas tous un hydrogène et que R1 et R4 ne représentent pas tous les deux un hydrogène.

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