C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 473/06 (2006.01) A61K 31/52 (2006.01) C07D 473/08 (2006.01) C07D 473/12 (2006.01)
Patent
CA 2107014
Disclosed are therapeutic agents for Parkinson's disease containing as an active ingredient a xanthine derivative or a pharmaceutically acceptable salt of the xanthine derivative, the xanthine derivative being represented by the following Formula (I): (see formula I) in which R1 and R2 represent independently methyl or ethyl; R3 represents independently hydrogen, lower alkyl, lower alkenyl, or lower alkynyl; R4 represents cycloalkyl, -(CH2)n-R5 (in which R5 represents substituted or unsubstituted aryl or a substituted or unsubstituted heterocyclic group; and n is an integer of 0 to 4), or (see formula II) (in which Y1 and Y2 represent independently hydrogen, halogen, or lower alkyl; and Z represents substituted or unsubstituted aryl, (see formula III) (in which R6 represents hydrogen, hydroxy, lower alkyl, lower alkoxy, halogen, nitro, or amino; and m represents an integer of 1 to 4), or a substituted or unsubstituted heterocyclic group); and X1 and X2 represent independently O or S. Disclosed is also a xanthine derivative represented by the following Formula (I-A): (see formula IV) in which R3a represents hydrogen or lower alkyl; Z a represents (see formula V) (in which at least one of R7, R8, and R9 represents lower alkyl or lower alkoxy and the others represent hydrogen; R10 represents hydrogen or lower alkyl) or (see formula VI) (in which R6 and m have the same meanings as defined above); and R1 and R2 have the same meanings as defined above, and a phamaceutically acceptable salt thereof.
Ichikawa Shunji
Koike Nobuaki
Nakamura Joji
Nonaka Hiromi
Shimada Junichi
Goudreau Gage Dubuc
Kyowa Hakko Kirin Co. Ltd.
LandOfFree
Therapeutic agent for parkinson's disease does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Therapeutic agent for parkinson's disease, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Therapeutic agent for parkinson's disease will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1595614