A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/137 (2006.01) A61P 1/16 (2006.01) A61P 3/10 (2006.01) A61P 37/06 (2006.01) A61P 43/00 (2006.01)
Patent
CA 2624909
It is intended to provide a novel therapeutic agent for an organ disease, particularly a therapeutic agent for a liver disease. It was found that a diaryl sulfide or diaryl ether derivative having a 2-amino-1,3-propanediol structure which is a sphingosine-1-phosphate receptor agonist represented by the general formula (1), a pharmaceutically acceptable salt or hydrate thereof is useful as the therapeutic agent for an organ disease, particularly the therapeutic agent for a liver disease.
L'invention concerne un nouvel agent thérapeutique destiné à une maladie d'organe, en particulier un agent thérapeutique destiné à une maladie hépatique. L'invention concerne un dérivé de sulfure de diaryle ou d'éther de diaryle présentant une structure 2-amino-1,3-propanediol qui est un agoniste du récepteur de sphingosine-1-phosphate de formule générale (1), un sel pharmaceutiquement acceptable ou un hydrate pharmaceutiquement acceptable de ce dérivé, utiles pour servir d'agent thérapeutique destiné à une maladie d'organe, en particulier à une maladie hépatique.
Kaneko Takashi
Kobayashi Eiji
Yasue Tokutarou
Kyorin Pharmaceutical Co. Ltd.
Norton Rose Or S.e.n.c.r.l.,s.r.l./llp
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