C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 317/32 (2006.01) A61K 31/16 (2006.01) A61K 31/40 (2006.01) A61K 31/4192 (2006.01) A61K 31/435 (2006.01) A61P 25/18 (2006.01) C07D 207/09 (2006.01) C07D 211/26 (2006.01) C07D 249/04 (2006.01)
Patent
CA 2611376
A compound of the formula (I): wherein R1,R2,R3, R4,Ar, A, n and m are defined herein, is disclosed as a GlyT1 inhibitor; pharmaceutical compositions containing the compound of the formula (I) are also disclosed as are their use in medicine, for example in the treatment of schizophrenia.
La présente invention a trait à un composé de formule (I), dans laquelle: R1, R2, R3, R4, Ar, A, n et m sont tels que définis dans la description, en tant qu'inhibiteur GlyT1; à des compositions pharmaceutiques contenant le composé de formule (I) ainsi qu'à leur utilisation en médecine, par exemple dans le traitement de la schizophrénie.
Blackaby Wesley Peter
Huscroft Ian Thomas
Keown Linda Elizabeth
Lewis Richard Thomas
Raubo Piotr Antoni
Merck Sharp & Dohme Limited
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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