C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 513/04 (2006.01) A61K 31/425 (2006.01) A61K 31/505 (2006.01)
Patent
CA 2222725
Compounds of formula (I) in which A is S(O)p or O; p is 0, 1 or 2; g is 0, 1, 2, 3, or 4; n is 2 or 3; and R1, R2, R3, R4 and R5 are optional substituents having utility in the treatment of central nervous system disorders, for example depression, anxiety, psychoses (for example schizophrenia), tardive dyskinesia, obesity, drug addiction, drug abuse, cognitive disorders, Alzheimer's disease, senile dementia, cerebral ischaemia, obsessive-compulsive behaviour, panic attacks, social phobias, eating disorders and anorexia, non- insulin dependent diabetes mellitus, hyperglycaemia, and stress.
Les composés de formule (I), dans lesquels A est S(O)¿p?, ou O; p vaut 0, 1 ou 2; g vaut 1, 2, 3 ou 4; n vaut 2 ou 3; et R¿1?, R¿2?, R¿3?, R¿4? et R¿5? sont des substituants éventuels et peuvent être utilisés dans le traitement des troubles du système nerveux central, tels que la dépression, l'angoisse, les psychoses (schizophrénie par exemple), les dyskinésies tardives, l'obésité, la toxicomanie, l'abus des médicaments, les troubles cognitifs, la maladie d'Alzheimer, la démence sénile, l'accident vasculaire cérébral, la psychoneurose obsessionnelle, les crises de panique, les phobies sociales, les troubles de l'alimentation et l'anorexie, le diabète sucré non insulino-dépendant, l'hyperglycémie et le stress.
Cheetham Sharon Crawford
Davies Roy Victor
Kerrigan Frank
Knoll Aktiengesellschaft
Robic
LandOfFree
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