C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 221/20 (2006.01) A61K 31/40 (2006.01) A61K 31/435 (2006.01) A61K 31/55 (2006.01) C07D 209/54 (2006.01) C07D 223/14 (2006.01)
Patent
CA 2148582
2148582 9411346 PCTABS00032 Compounds of formula (I) and pharmaceutically acceptable salts thereof in which m is an integer from 1 to 3; n is an integer from 2 to 6; R1 is phenyl optionally substituted by one or more substituents selected from halo, hydroxy, alkoxy, alkanoyl, alkyl, halogenated alkyl, alkylthio, alkylsulphinyl, alkylsulphonyl, cyano, nitro, optionally substituted amino, optionally substituted sulphamoyl, optionally substituted carbamoyl or phenyl, or R1 is naphthyl; R2 is H, alkyl or phenyl; R3 is H, alkyl, alkenyl or alkoxyalkyl; R4 is H or hydroxy; and R5 is H or together with R4 represents a bond; have utility in the treatment of obesity and affective disorders such as depression and anxiety.
Harris Paul John
Kerrigan Frank
Boots Company Plc (the)
Mccarthy Tetrault Llp
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