Therapeutic agents

A - Human Necessities – 61 – K

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167/226

A61K 31/47 (2006.01)

Patent

CA 1171789

Abstract Therapeutic Agents Therapeutic compositions which comprise as an active ingredient a quinolone of the general formula Image I wherein n is 0, 1 or 2 and either (a) R2 is hydrogen and R1 is methyl or ethyl, or (b) R2 is methyl and R1 is ethyl, provided that, when R1 is ethyl, n is 1 or 2, together with a pharmaceutically acceptable carrier. The compositions have antihypertensive activity and may be used for treating hypertension in warm blooded animals including man. Administration may be enteral or parenteral; enteral administration, especially oral administration, is preferred.

415369

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