Therapeutic agents, and methods of making and using the same

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 519/00 (2006.01) A61K 31/55 (2006.01) A61P 31/04 (2006.01) C07D 471/04 (2006.01) C07D 498/04 (2006.01)

Patent

CA 2658506

In part, the present invention is directed towards compounds with FAB I inhibiting properties. Such compounds may also inhibit other enzymes, including those similar to FAB I either structurally or functionally, for example FAB K. Said compounds and compositions thereof may be used to treat bacterial infections. Said compounds may also be used to disinfect an inanimate surface by contacting the antibacterial compound to the inanimate surface. Kits comprising said compositions that include the disclosed compounds are also provided, along with instructions for use thereof.

La présente invention concerne en partie des composés dotés de propriétés inhibitrices vis-à-vis de FAB I. De tels composés peuvent également inhiber d'autres enzymes, y compris celles qui sont similaires à FAB I, soit du point de vue structurel, soit du point de vue fonctionnel, par exemple FAB K. Lesdits composés et compositions peuvent donc être employés dans le traitement d'infections bactériennes. Lesdits composés peuvent également être employés pour désinfecter une surface inanimée par mise en contact du composé antibactérien avec ladite surface inanimée. La présente invention a également pour objet des kits comprenant lesdites compositions qui incluent les composés selon l'invention, ainsi que des instructions permettant leur utilisation.

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