C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/06 (2006.01) A61K 31/335 (2006.01) A61K 38/03 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) A61K 38/16 (2006.01) A61P 35/00 (2006.01) C07D 303/16 (2006.01) C07D 405/14 (2006.01) C07K 4/00 (2006.01) C07K 5/02 (2006.01) C07K 5/06 (2006.01) C07K 5/083 (2006.01) C07K 5/09 (2006.01) C07K 5/10 (2006.01) C07K 5/103 (2006.01) C07K 14/00 (2006.01) C07K 14/81 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2426703
The present invention provides angiogenesis inhibitor compounds comprising a MetAP-2 inhibitory core coupled to a peptide, as well as pharmaceutical compositions comprising the angiogenesis inhibitor compounds and a pharmaceutically acceptable carrier. The present invention also provides methods of treating an angiogenic disease, e.g.,cancer, in a subject by administering to the subject a therapeutically effective amount of one or more of the angiogenesis inhibitor compounds of the invention.
La présente invention concerne des composés d'inhibiteur de l'angiogenèse qui renferment un noyau inhibiteur de la MetAP-2 couplé à un peptide, ainsi que des compositions pharmaceutiques comprenant les composés d'inhibiteur de l'angiogenèse et un support pharmaceutiquement acceptable. Cette invention concerne également des méthodes de traitement d'une maladie angiogénique, le cancer <i>par exemple</i> chez un individu, qui consistent à administrer à l'individu une quantité efficace du point de vue thérapeutique d'au moins un des composés d'inhibiteur de l'angiogenèse selon l'invention.
Arico-Muendel Christopher C.
Birktoft Jens
Cook Charles Michael
Lee Lily
Morgan Barry
Borden Ladner Gervais Llp
Praecis Pharmaceuticals Incorporated
LandOfFree
Therapeutic agents and methods of use thereof for the... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Therapeutic agents and methods of use thereof for the..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Therapeutic agents and methods of use thereof for the... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1471023