A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/45 (2006.01) A61K 38/19 (2006.01) A61P 35/00 (2006.01) A61P 37/02 (2006.01)
Patent
CA 2551189
The present invention relates generally to therapeutic agents and methods which enhance or otherwise maintain a state of immune tolerance in a subject. The present invention further provides agents and methods for preventing or at least delaying onset of an autoimmune disease such as but not limited to autoimmune diabetes. Furthermore, the agents and methods of the present invention are useful in enhancing the effectiveness of vaccine regimes such as against cancer cells or pathogenic organisms and viruses or for generally enhancing the immune responsiveness against such entities. The present invention further enables the prevention of pathogenic agent-induced autoimmune conditions.
L'invention concerne de façon générale des agents thérapeutiques ainsi que des procédés qui stimulent ou sinon maintiennent un état de tolérance immunitaire chez un sujet. De plus, l'invention concerne des agents et des procédés destinés à prévenir, ou du moins retarder l'apparition d'une maladie auto-immune telle que, mais non exclusivement, le diabète. Par ailleurs, les agents et procédés de l'invention sont utilisés pour stimuler l'efficacité des vaccins, notamment ceux qui agissent contre les cellules cancéreuses ou les organismes pathogènes et les virus, ou, de façon générale, pour stimuler la réactivité immunitaire vis à vis de ces entités. L'invention concerne également la prévention d'états auto-immuns induits pars des agents pathogènes.
Fancke Ben
Harrison Len
O'keeffe Meredith
Shortman Ken
Steptoe Ray
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
The Walter And Eliza Hall Institute Of Medical Research
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