Therapeutic agents for apoptosis-related diseases

A - Human Necessities – 61 – K

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A61K 38/17 (2006.01) A61K 38/18 (2006.01)

Patent

CA 2343746

It is found out that a protein belonging to the midkine (MK) family inhibits the induction of apoptosis caused by anticancer agents, ultraviolet irradiation and ischemic stress. This finding makes it possible to provide novel drugs containing the protein belonging to the MK family as the active ingredient for treating and preventing any diseases caused by apoptosis, for example, heart diseases, renal diseases, nervous diseases or liver diseases.

On a découvert qu'une protéine appartenant à la famille de la midkine (MK) inhibe l'induction de l'apoptose due à des agents anticancéreux, au rayonnement ultraviolet, et aux accidents ischémiques. Cette découverte permet donc d'obtenir de nouveaux médicaments contenant, comme principe actif, la protéine appartenant à la famille MK, ces nouveaux médicaments étant destinés à traiter et à prévenir toute maladie provoquée par l'apoptose, notamment les maladies cardiaques, rénales, nerveuses, ou les maladies du foie.

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