Therapeutic agents for low hdl-cholesterolemia

Details Therapeutic agents for low hdl-cholesterolemia Therapeutic agents for low hdl-cholesterolemia

A - Human Necessities

61

K

A61K 38/57 (2006.01) A61K 31/336 (2006.01) A61K 38/06 (2006.01) A61K 38/55 (2006.01) A61P 3/06 (2006.01) A61P 9/10 (2006.01) C12Q 1/02 (2006.01)

Patent

CA 2463395

It is intended to provide drugs ameliorating hypo-HDL cholesterolemia, preventives/remedies for arteriosclerosis, and a method of preventing/treating these diseases/symptoms targeting HDL without needing any genetic engineering techniques. Namely, clinically useful drugs ameliorating hypo-HDL cholesterolemia and preventives/remedies for arteriosclerosis which contain a cysteine protease inhibitor as the active ingredient and thus can enhance the expression dose of ABCA1 and increase HDL in the blood without employing any genetic engineering techniques.

L'invention porte sur des médicaments permettant d'améliorer l'hypocholestérolémie HDL, sur des agents prophylactiques et des remèdes pour l'artériosclérose et sur un procédé de prévention et de traitement de ces maladies et symptômes ciblant HDL, et cela sans avoir recours à des techniques de génie génétique. Ces médicaments utiles en clinique destinés à améliorer l'hypocholestérolémie HDL, ainsi que les agents prophylactiques et remèdes pour l'artériosclérose, contiennent notamment un inhibiteur de la cystéine protéase agissant comme ingrédient actif et peuvent ainsi augmenter la dose d'expression d'ABCA1 ainsi que le HDL dans le sang sans utiliser de techniques du génie génétique.

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