Therapeutic and diagnostic agents

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 4/12 (2006.01) A61K 38/28 (2006.01) A61P 37/00 (2006.01) A61P 43/00 (2006.01) C07K 7/08 (2006.01) C07K 14/62 (2006.01)

Patent

CA 2574665

The present invention relates generally to the field of immunotherapy and immunodiagnosis of autoimmune conditions. More particularly, the present invention provides agents which are recognized by or are specific for proinsulin- or insulin-sensitized T-cells. The present invention further contemplates the use of the these agents in therapeutic and diagnostic applications for Type 1 diabetes.

L'invention concerne généralement le domaine de l'immunothérapie et de l'immunodiagnostic de maladies auto-immunes. D'une manière plus spécifique, l'invention concerne des agents qui sont reconnus par des lymphocytes T sensibilisés à l'insuline ou à la proinsuline ou qui sont spécifiques de ces lymphocytes T. L'invention concerne également l'utilisation de ces agents dans des applications thérapeutiques et diagnostiques destinées au diabète du Type 1.

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