C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2270171
The present invention relates generally to therapeutic and diagnostic agents. More particularly, the present invention provides therapeutic molecules capable of modulating signal transduction such as but not limited to cytokine- mediated signal transduction. The molecules of the present invention are useful, therefore, in modulating cellular responsiveness to cytokines as well as other mediators of signal transduction such as endogenous or exogenous molecules, antigens, microbes and microbial products, viruses or components thereof, ions, hormones and parasites.
L'invention concerne de manière générale des agents thérapeutiques et diagnostiques, et plus particulièrement des molécules thérapeutiques capables de moduler la transduction de signal, notamment mais non exclusivement la transduction de signal via les cytokines. Ces molécules sont donc utiles pour moduler la réceptivité cellulaire aux cytokines ainsi qu'à d'autres médiateurs de transduction de signal, tels que les molécules endogènes ou exogènes, les antigènes, les microbes et produits microbiens, virus ou composants de ces derniers, ions, hormones et parasites.
Alexander Warren S.
Hilton Douglas J.
Metcalf Donald
Nicholson Sandra E.
Nicola Nicos A.
Fetherstonhaugh & Co.
The Walter And Eliza Hall Institute Of Medical Research
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