C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
167/139, 530/15.
C07K 16/18 (2006.01) A61K 39/395 (2006.01) A61K 38/00 (2006.01)
Patent
CA 1260828
Abstract of the Disclosure Fab or Fc fragment of human IgG which is obtainable by enzymatic digestion of the human IgG is reduced by a reducing agent to sever a interchain of disulfide bonds therein and then blocked the SH radicals formed with alkyl group which may comtain other group . The resulting alkylated Fab and Fc fragments display therapeutic and prophylactic action for gastrointestinal ulcers by the oral or parenteral administration.
457425
Fukushima Tsunekazu
Iwai Masakazu
Yokoyama Kazumasa
Fetherstonhaugh & Co.
Welfide Corporation
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