Therapeutic antimicrobial polypeptides, their use and...

Details Therapeutic antimicrobial polypeptides, their use and... Therapeutic antimicrobial polypeptides, their use and...

C - Chemistry, Metallurgy

12

N

167/135, 167/103

C12N 1/06 (2006.01) C07K 14/435 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1327311

ABSTRACT OF THE DISCLOSURE A novel class of antimicrobial agents for animal species including cecropins, attacins, lysozymes, phage derived polypeptides, such as those transcribed from gene 13 of phage 22, an S protein from lambda phage, and an E protein from phage PhiX174, as well as, synthetically derived polypeptides of similar nature. The antimicrobial agents can be used to treat microbial infections and as components of medicinal compositions. The genes encoding for such antimicrobial agents can be used to transform animal cells, especially embryonic cells. The transformed animals including such antimicrobial cells are also included.

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