Therapeutic combinations of antihypertensive and...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/505 (2006.01) A61K 31/40 (2006.01) A61K 38/55 (2006.01) A61P 5/50 (2006.01) A61P 9/00 (2006.01) A61P 17/06 (2006.01) A61P 27/00 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2401854

The invention concerns the use of a combination of an anti-angiogenic agent and an anti-hypertensive agent for use in the manufacture of a medicament for the treatment of a disease state associated with angiogenesis in a warm- blooded mammal, such as a human being. The invention also relates to pharmaceutical compositions comprising an anti-angiogenic agent and an anti- hypertensive agent, to kits thereof and to a method of treatment of a disease state associated with angiogenesis which comprises the administration of an effective amount of a combination of an anti-angiogenic agent and an anti- hypertensive agent to a warm-blooded animal, such as a human being.

L'invention concerne l'utilisation d'une combinaison d'un agent hypertenseur et d'un agent anti-angiogénique pour la fabrication d'un médicament destiné au traitement d'un état maladif associé à l'angiogénèse chez un mammifère à sang chaud, tel que l'être humain. L'invention concerne aussi des compositions pharmaceutiques comprenant un agent anti-angiogénique et un agent hypertenseur, des nécessaires les contenant ainsi qu'une méthode de traitement d'un état maladif associé à l'angiogénèse qui consiste à administrer une quantité efficace d'une combinaison d'un agent anti-angiogénique et d'un agent hypertenseur à un animal à sang chaud, tel qu'un être humain.

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