Therapeutic composition for hepatic encephalopathy

A - Human Necessities – 61 – K

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167/199, 167/228

A61K 31/70 (2006.01) A61K 31/13 (2006.01) A61K 31/34 (2006.01) A61K 31/38 (2006.01) A61K 31/44 (2006.01)

Patent

CA 1336072

A pharmaceutical composition for the treatment of hyperammonemia which comprises a valiolamine compound of the formula Image [I] wherein A means an acyclic hydrocarbon group of 1 to 10 carbon atoms which may optionally be substituted by hydroxy, phenoxy, thienyl, furyl, pyridyl, cyclohexyl or optionally substituted phenyl; a 5- or 6-membered cyclic hydrocarbon group which may optionally be substituted by hydroxy, hydroxymethyl, methyl or amino; or a saccharide residue or a pharmaceutically acceptable salt thereof, the use of said valiolamine compound of the formula [I] or a pharmaceutically acceptable salt thereof in the preparation of a medicine for the treatment of hyperammonemia, and a method for the treatment of hyperammonemia which comprises administrating a valiolamine compound of the formula [I] or a pharmaceutically acceptable salt thereof.

600944

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