A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/16 (2006.01) A61K 9/48 (2006.01) A61K 31/545 (2006.01) A61P 31/04 (2006.01)
Patent
CA 2606386
The present invention provides oral formulations of poorly bioavailable and/or poorly absorbable, and/or poorly water soluble therapeutic agents. The invention features pharmaceutical composition including a biopolymer, a therapeutic agent, for example an antimicrobial agent such as ceftriaxone, and an absorption enhancer, for example a polyoxyethylene alkyl ether absorption enhancer. Methods of making and using the pharmaceutical compositions is also described.
L'invention se rapporte à des formulations orales d'agents thérapeutiques peu biodisponibles, et/ou peu absorbables, et/ou peu hydrosolubles. Cette invention concerne également des compositions pharmaceutiques comprenant un biopolymère, un agent thérapeutique, par exemple un agent antimicrobien tel que la ceftriaxone, et un renforçateur d'absorption, par exemple un alkyléther de polyoxyéthylène. La présente invention se rapporte en outre à des procédés de production et d'utilisation de ces nouvelles compositions pharmaceutiques.
Gowan Walter J. Jr.
Keith Dennis D.
O'connor Sandra
Cubist Pharmaceuticals Inc.
Gowling Lafleur Henderson Llp
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