A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01) A61K 39/395 (2006.01) A61K 41/00 (2006.01) C07K 16/30 (2006.01) C07K 16/42 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2333221
The invention concerns methods and compositions for stimulating a host's immune response, particularly for the treatment of cancer. The methods and compositions according to the invention use binding agents such as antibodies to generate an immune response to a predetermined soluble antigen. In accordance with the invention, the binding agent-soluble antigen complex alters the immunogenic condition of the host by generating new immunogens that are recognizable by the immune system. This leads to a humoral and/or cellular immune response.
L'invention concerne des méthodes et des compositions permettant de stimuler une réponse immunitaire chez un hôte et destinées notamment au traitement du cancer. Ces méthodes et ces compositions font intervenir des liants tels que des anticorps, de façon à provoquer une réponse immunitaire à un antigène soluble prédéterminé. Selon l'invention, le complexe formé par le liant et l'antigène soluble modifie l'état immunogène de l'hôte en produisant de nouveaux immunogènes reconnaissables par le système immunitaire, ce qui entraîne une réponse immunitaire humorale et/ou cellulaire.
Baum Richard P.
Madiyalakan Ragupathy
Noujaim Antoine A.
Schultes Birgit
Altarex Corp.
Altarex Medical Corp.
Parlee Mclaws Llp
LandOfFree
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