C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 231/14 (2006.01) A61K 31/4155 (2006.01) A61P 25/28 (2006.01) C07D 401/04 (2006.01) C07D 409/04 (2006.01) C07D 409/14 (2006.01) C07D 417/14 (2006.01) C07D 451/06 (2006.01) C07D 453/04 (2006.01)
Patent
CA 2644068
The invention provides a compound of formula (I) wherein R1-R6, X, Y, and B have any of the values described herein, as well as salts of such compounds, compositions comprising such compounds, and therapeutic methods that comprise the administration of such compounds. The compounds are inhibitors of MAO-B enzyme function and are useful for improving cognitive function and for treating psychiatric disorders in animals.
La présente invention concerne un composé de formule (I) dans laquelle R1-R6, X, Y et B ont l'une quelconque des significations indiquées dans le présent document, ainsi que les sels de tels composés, des compositions comprenant de tels composés et des méthodes thérapeutiques qui comprennent l'administration de tels composés. Les composés selon l'invention sont des inhibiteurs de la fonction de l'enzyme MAO-B et sont utiles pour améliorer les fonctions cognitives et pour traiter les troubles psychiatriques chez l'animal.
Bourtchouladze Rusiko
Kaplan Alan P.
Keenan Terence P.
Mcriner Andrew
Scott Roderick E.m.
Helicon Therapeutics Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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