Therapeutic delivery of carbon monoxide

A - Human Necessities – 01 – N

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A01N 1/02 (2006.01) A61K 31/416 (2006.01) A61K 31/69 (2006.01) A61K 45/06 (2006.01) A61P 7/04 (2006.01) A61P 9/04 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01) A61P 11/00 (2006.01) A61P 29/00 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) A61P 41/00 (2006.01)

Patent

CA 2534415

Boranocarbonates are described for administration to a human or other mammal for delivery of carbon monoxide. The boranocarbonate is a compound or ion adapted to make CO available for physiological effect, and may be administered with a guanylate cyclase stimulant or stabilizer. The physiological effect may be stimulation of neurotransmission, vasodilation or smooth muscle relaxation.

L'invention concerne des boranocarbonates destinés convenant pour l'administration à un humain ou à un autre mammifère, afin de permettre la délivrance de monoxyde de carbone. Le boranocarbonate est un composé ou un ion conçu pour rendre le CO assimilable afin qu'il produise un effet physiologique, et peut être administré conjointement à un stimulant ou à un stabilisateur de la guanylate cyclase. L'effet physiologique peut être une stimulation de la neurotransmission, de la vasodilatation ou de la relaxation des muscles lisses.

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