A - Human Necessities – 61 – M
Patent
A - Human Necessities
61
M
A61M 31/00 (2006.01) A61F 2/82 (2006.01) A61K 9/00 (2006.01) A61L 27/54 (2006.01) A61L 31/16 (2006.01) A61L 31/04 (2006.01)
Patent
CA 2587820
The present invention regards the delivery of therapeutic at a target site. Systems that employ the present invention may employ a medical device sized to be inserted into a target site, a driving layer covering at least a portion of an accessible surface of the medical device, and a therapeutic interfaced with at least a portion of the driving layer. In this system, the driving layer may have a material characteristic that serves to release the therapeutic from the medical device when the medical device is at the target site. Other systems that employ the invention may also have properties that include having a driving layer with a higher solubility than the therapeutic at the target site, a medical device that is hydrophobic while the therapeutic is hydrophilic, and a coating covering at least a portion of the therapeutic.
La présente invention concerne l~administration d~un agent thérapeutique sur un site cible. Les systèmes qui utilisent la présente invention peuvent employer un dispositif médical dont la taille lui permet d~être inséré dans un site cible, une couche de transmission couvrant au moins une partie d~une surface accessible du dispositif médical et un agent thérapeutique faisant l~interface avec au moins une partie de la couche de transmission. Dans ce système, la couche de transmission peut présenter une caractéristique matérielle servant à libérer l~agent thérapeutique du dispositif médical lorsque celui-ci atteint le site cible. D~autres systèmes ayant recours à l~invention peuvent également posséder des propriétés comprenant la présence d~une couche de transmission ayant une solubilité supérieure à celle de l~agent thérapeutique sur le site cible, un dispositif médical hydrophobe lorsque l~agent thérapeutique est hydrophile et un revêtement couvrant au moins une partie de l~agent thérapeutique.
Epstein Samuel J.
Naimark Wendy
Ostrovsky Irina
Panos Anastasia
Boston Scientific Limited
Mccarthy Tetrault Llp
Scimed Life Systems Inc.
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