Therapeutic heterocyclic compounds

Details Therapeutic heterocyclic compounds Therapeutic heterocyclic compounds

C - Chemistry, Metallurgy

07

D

C07D 311/24 (2006.01) A61K 31/497 (2006.01) A61K 31/5377 (2006.01) C07D 215/233 (2006.01) C07D 215/48 (2006.01) C07D 215/50 (2006.01) C07D 311/58 (2006.01) C07D 311/74 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/06 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 413/06 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2434152

Provided herein is a compound having the formula (I) wherein said compounds are useful for the treatment of psychiatric disorders including but not limited to depression, generalized anxiety, eating disorders, dementia, panic disorder, and sleep disorders. The compounds may also be useful in the treatment of gastrointestinal disorders, cardiovascular regulation, motor disorders, endocrine disorders, vasospasm and sexual dysfunction. The compounds are 5HT1B and 5HT1D antagonists.

L'invention concerne un composé ayant la formule (I) où ces composés sont utiles pour traiter des troubles psychiatriques comme la dépression, une anxiété généralisée, des troubles de l'alimentation, la démence, le trouble panique, des troubles du sommeil etc. Ces composés peuvent également être utiles pour traiter des troubles gastro-intestinaux, une régulation cardiovasculaire, le trouble moteur, des troubles endocriniens, le spasme vasculaire et un dysfonctionnement sexuel. Ces composés sont des antagonistes 5HT¿1B? et 5HT¿1D?.

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