Therapeutic microparticles

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/16 (2006.01) A61K 47/34 (2006.01) G01N 3/08 (2006.01) G01N 15/00 (2006.01)

Patent

CA 2548106

Biodegradable, compression resistant microparticles adapted for injection through a catheter system, such as is useful for selective embolization procedures. The microparticles can optimally be neutrally buoyant relative to a target bodily fluid. Various active agents may be included in the microparticles, such an anesthetic which can reduce pain during an embolization procedure. The invention further comprises methods and equipment for testing and delivering compression resistant microparticles.

La présente invention se rapporte à des microparticules biodégradables et résistantes à la compression, qui sont adaptées pour être injectées par l'intermédiaire d'un système de cathéter, tels les systèmes servant aux procédures d'embolisation sélective. Les microparticules selon l'invention peuvent idéalement présenter une densité équivalente à celle d'un fluide corporel cible. Les microparticules peuvent renfermer divers agents actifs, tels qu'un anesthésique pouvant réduire la douleur pendant une procédure d'embolisation. L'invention concerne également des procédés et du matériel permettant de tester et d'administrer des microparticules résistantes à la compression.

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