C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/435 (2006.01) A61K 38/18 (2006.01) A61P 3/04 (2006.01) A61P 5/04 (2006.01) C07K 14/52 (2006.01) C12N 9/12 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2514071
The present invention relates generally to a ligand for a protein associated with modulating obesity, diabetes and metabolic energy levels in animals including humans. More particularly, the present invention provides a ligand of the protein, Beacon, and its homologs. The identification of a Beacon ligand permits the identification of agents which agonize or antagonize the Beacon-ligand interaction and, hence, the development of therapeutic molecules useful in modulating obesity, diabetes and/or energy imbalance.
La présente invention concerne généralement un ligand destiné à une protéine associée à la modulation de l'obésité, de diabètes et de niveaux d'énergie métabolique chez des animaux, y compris, les êtres humains. Plus spécifiquement, cette invention a trait à un ligand de la protéine, Beacon, et à ses homologues. L'identification d'un ligand Beacon permet l'identification d'agents qui augmentent ou diminuent l'interaction Beacon-ligand et, donc, le développement de molécules thérapeutiques utilisées dans la modulation de l'obésité, de diabètes et/ou de déséquilibre d'énergie.
Collier Greg
Kerr-Bayles Lyndal
Walder Ken
Autogen Research Pty Ltd
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Deakin University
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