Therapeutic or preventive agents for ischemic heart disease...

A - Human Necessities – 61 – K

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A61K 45/00 (2006.01) A61K 31/496 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01) A61P 9/10 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2591474

[PROBLEMS] To provide a remedy or a preventive for ischemic cardiac disease or ischemic cardiac myopathy which has an effect of preventing the progress of myocardial necrosis due to dysfunction in a cardiac tissue suffering from reperfusion injury or protecting a cardiac tissue. [MEANS FOR SOLVING PROBLEMS] A remedy or a preventive for ischemic cardiac disease or ischemic cardiac myopathy which contains an upregulator compound for NAIP gene as the active ingredient.

L'invention entend proposer une thérapie ou une prévention des maladies cardiaques ischémiques ou des myopathies cardiaques ischémiques ayant pour effet d'empêcher la progression de la nécrose du myocarde à la suite d'un dysfonctionnement d'un tissu cardiaque souffrant d'une blessure par nouvelle perfusion ou de protéger un tissu cardiaque. L'invention concerne donc une thérapie ou une prévention des maladies cardiaques ischémiques ou des myopathies cardiaques ischémiques contenant un composé régulateur de renforcement pour gène NAIP comme ingrédient actif.

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