Therapeutic or prophylactic agent for arthritis

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 9/88 (2006.01) C12N 5/077 (2010.01) A61K 38/17 (2006.01) A61P 19/02 (2006.01) C07K 14/465 (2006.01) C07K 14/47 (2006.01) C07K 14/575 (2006.01) C12Q 1/02 (2006.01) C12Q 1/527 (2006.01)

Patent

CA 2561530

It is intended to provide a novel remedy or a preventive for arthritis such as arthritis deformans. More specifically speaking, a remedy or a preventive for arthritis such as arthritis deformans or a joint cartilage cell growth promoter characterized by containing, as the active ingredient, a guanyl cyclase B (GC-B) activator; a method of inhibiting arthritis or a method of promoting the growth of joint cartilage cells by activating GC-B; or a method of screening a joint cartilage cell growth promoter or a remedy for arthritis by using GC-B activity as an indication.

Il est prévu de fournir un remède novateur ou un médicament préventif pour l'arthrite telle que l'arthritis deformans (polyarthrite rhumatoïde). Plus particulièrement, un remède ou un médicament préventif destiné à l'arthrite telle que l'arthritis deformans ou un promoteur de croissance de cellules de cartilage articulaire, caractérisé en ce qu'il contient un activateur de guanyl cyclase B (GC-B), un procédé d'inhibition de l'arthrite ou un procédé favorisant la croissance de cellules de cartilage articulaire en activant la GC-B ou un procédé de dépistage d'un promoteur de croissance des cellules de cartilage articulaire ou un remède pour l'arthrite en utilisant l'activité de la GC-B comme indication.

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