Therapeutic or prophylactic agent for diabetes, obesity,...

A - Human Necessities – 61 – K

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A61K 31/18 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2731378

Disclosed is a therapeutic or prophylactic agent for diabetes, obesity, dyslipidemia or metabolic syndrome, which can exhibit significant efficacy at a low dose and does not produce a heart rate increasing activity or a QT interval extending activity which is an adverse side effect on the circulatory system. Specifically disclosed is a therapeutic or prophylactic agent for diabetes, obesity, dyslipidemia or metabolic syndrome, which comprises a benzylamine derivative represented by formula or a pharmaceutically acceptable acid addition salt thereof.

L'invention porte sur un agent thérapeutique ou prophylactique pour le diabète, l'obésité, la dyslipidémie ou un syndrome métabolique, qui peut présenter une efficacité significative à une dose faible et qui ne produit pas d'activité augmentant la fréquence cardiaque ou dactivité étendant l'intervalle QT, qui est un effet secondaire néfaste sur le système circulatoire. L'invention porte spécifiquement sur un agent thérapeutique ou prophylactique pour le diabète, l'obésité, la dyslipidémie ou un syndrome métabolique, qui comprend un dérivé de benzylamine représenté par la formule ou un sel d'addition avec les acides pharmaceutiquement acceptables correspondants.

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