A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 29/08 (2006.01) A61L 29/16 (2006.01) A61L 31/10 (2006.01) A61L 31/16 (2006.01)
Patent
CA 2613058
This invention provides a high-solids therapeutic composition for coating a medical device comprising: (a) a first material which is a hydrophilic therapeutic agent; and (b) a second material which includes a hydrophobic polymer and an emulsifying surfactant, wherein the composition is in a singular stable phase. Also provided is a mold-cast medical device, said medical device comprising a cured mixture of: (a) a first material which is a hydrophilic therapeutic agent; and (b) a second material which includes a hydrophobic polymer and an emulsifying surfactant, wherein the mixture forms a high-solids device. Further provided is an injectable polymer comprising: (a) a first material which is a hydrophilic therapeutic agent; and (b) a second material which includes a hydrophobic polymer and an emulsifying surfactant, wherein the polymer is in a singular stable phase.
Cette invention concerne une composition thérapeutique à haute teneur en matières solides servant à enduire un matériel médical comprenant : (a) une première matière qui est un agent thérapeutique hydrophile ; et (b) une seconde matière qui comprend un polymère hydrophobe et un tensioactif émulsifiant, ladite composition étant sous forme d'une seule phase stable. L'invention concerne également un matériel médical coulé dans un moule, ledit matériel médical comprenant un mélange durci constitué de : (a) une première matière qui est un agent thérapeutique hydrophile ; et (b) une seconde matière qui comprend un polymère hydrophobe et un tensioactif émulsifiant, ledit mélange formant un matériel à teneur en matières solides élevée. L'invention concerne en outre un polymère injectable comprenant : (a) une première matière qui est un agent thérapeutique hydrophile ; et (b) une seconde matière qui comprend un polymère hydrophobe et un tensioactif émulsifiant, ledit polymère étant sous forme d'une seule phase stable.
Epstein Samuel J.
Naimark Wendy
Boston Scientific Limited
Boston Scientific Scimed Inc.
Mccarthy Tetrault Llp
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