Therapeutic peptide derivatives

Details Therapeutic peptide derivatives Therapeutic peptide derivatives

C - Chemistry, Metallurgy

07

K

C07K 14/435 (2006.01) A61K 38/08 (2006.01) A61K 38/17 (2006.01) A61K 38/22 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/655 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2168113

Peptide derivatives containing one or more substituents separately linked by an amide, amino or sulfonamide bond to an amino group on either the N-terminal end or side chain of a biologically active peptide moiety. The peptide derivatives have relatively enhanced biological activity when compared to the corresponding peptide alone.

L'invention concerne des dérivés peptidiques contenant un ou plusieurs substituants liés chacun par une liaison amide, amino ou sulfonamide à un groupe amino, soit sur l'extrémité N-terminale, soit sur la chaîne latérale d'une fraction peptidique biologiquement active. Les dérivés peptidiques ont une activité biologique relativement plus importante lorsqu'on les compare au peptide correspondant seul.

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